Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 19/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171883 | 0.87 | RPS6KB1 (0.71) | RPS6KB1 | |
| SCHEMBL18176555 | 0.85 | RPS6KB1 (0.60) | RPS6KB1 | |
| SCHEMBL18176278 | 0.85 | RPS6KB1 (0.72) | RPS6KB1 | |
| SCHEMBL18176551 | 0.85 | RPS6KB1 (0.59) | RPS6KB1CSF1R | |
| Hydrochloric Acid SCHEMBL18171872 | 0.84 | RPS6KB1 (0.58) | RPS6KB1CSF1R | |
| SCHEMBL18176583 | 0.80 | RPS6KB1 (0.61) | RPS6KB1CSF1R | |
| SCHEMBL18176290 | 0.77 | RPS6KB1 (0.72) | RPS6KB1 | |
| SCHEMBL18176396 | 0.77 | RPS6KB1 (0.72) | RPS6KB1 | |
| SCHEMBL18176580 | 0.76 | RPS6KB1 (0.62) | RPS6KB1 | |
| SCHEMBL18176399 | 0.76 | RPS6KB1 (0.58) | RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |