Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 17/20 | 0.61 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171883 | 0.88 | RPS6KB1 (0.71) | RPS6KB1 | |
| SCHEMBL18176551 | 0.88 | RPS6KB1 (0.59) | RPS6KB1CSF1R | |
| Hydrochloric Acid SCHEMBL18171872 | 0.87 | RPS6KB1 (0.58) | RPS6KB1CSF1R | |
| SCHEMBL18176555 | 0.83 | RPS6KB1 (0.60) | RPS6KB1 | |
| SCHEMBL18176278 | 0.83 | RPS6KB1 (0.72) | RPS6KB1 | |
| SCHEMBL18176559 | 0.82 | RPS6KB1 (0.61) | RPS6KB1 | |
| SCHEMBL780665 | 0.80 | ROCK2 (0.58) | ROCK2CYP2C9ROCK1CDC42BPA | |
| SCHEMBL18176560 | 0.80 | RPS6KB1 (0.58) | RPS6KB1CSF1R | |
| SCHEMBL20445828 | 0.76 | RPS6KB1 (1.00) | RPS6KB1 | |
| SCHEMBL18176579 | 0.75 | RPS6KB1 (0.73) | RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |