Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | UBE2N | P61088 | 1/20 | 0.62 |
| ▸ | IDH1 | O75874 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RPA1 | P27694 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13532199 | 0.88 | MAPT (0.90) | PTGER4MEN1KMT2ANPC1MAPT | |
| SCHEMBL13870863 | 0.85 | MEN1 (1.00) | PTGER4MEN1KMT2ANPC1MAPT | |
| SCHEMBL6403077 | 0.84 | KMT2A (0.81) | PTGER4MEN1KMT2ANPC1MAPT | |
| SCHEMBL13532193 | 0.82 | MEN1 (0.74) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL14292254 | 0.82 | MAPT (0.76) | PTGER4MEN1KMT2ANPC1MAPT | |
| SCHEMBL27180675 | 0.81 | MAPT (0.82) | MEN1KMT2ANPC1MAPTTP53 | |
| SCHEMBL30927002 | 0.81 | MAPT (0.82) | MEN1KMT2ANPC1MAPTTP53 | |
| SCHEMBL31556104 | 0.80 | RAD51 (0.69) | PTGER4MEN1KMT2ANPC1MAPT | |
| SCHEMBL31556105 | 0.80 | RAD51 (0.69) | PTGER4MEN1KMT2ANPC1MAPT | |
| SCHEMBL13532177 | 0.79 | MAPT (0.72) | PTGER4MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016172545-A1 | CASTRATION-RESISTANT PROSTATE CANCER | NUTECH VENTURES (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | UGDH, G6PD, DPYD | PTGER4 3674/4885MEN1 2328/4885KMT2A 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.