Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138655 | 0.88 | FFAR4 (0.49) | L3MBTL1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL18178489 | 0.88 | L3MBTL1 (0.48) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18178168 | 0.88 | KDM4E (0.45) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18182151 | 0.87 | FFAR4 (0.43) | KDM4EL3MBTL1PTGER1PTGDR2HSD17B10 | |
| SCHEMBL18178111 | 0.86 | MRGPRX4 (0.50) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18178053 | 0.86 | MRGPRX4 (0.50) | KDM4EL3MBTL1PTGDR2HSD17B10HPGD | |
| SCHEMBL18178061 | 0.86 | MAPT (0.50) | KDM4EL3MBTL1HPGDMAPTHTT | |
| SCHEMBL18178386 | 0.86 | PTGDR2 (0.43) | KDM4EPTGER1PTGDR2HSD17B10HPGD | |
| SCHEMBL18178109 | 0.85 | L3MBTL1 (0.41) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18182760 | 0.85 | PTGDR2 (0.42) | KDM4EPTGER1PTGDR2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | KDM4E 2107/4885L3MBTL1 401/4885PTGER1 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.