Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178490 | 0.90 | KDM4E (0.38) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18178168 | 0.90 | KDM4E (0.45) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18182154 | 0.89 | MAPT (0.36) | KDM4EL3MBTL1HPGDHSD17B10MAPT | |
| SCHEMBL18178070 | 0.88 | MRGPRX4 (0.47) | KDM4EL3MBTL1MRGPRX4HPGDHSD17B10 | |
| SCHEMBL18178080 | 0.88 | L3MBTL1 (0.41) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18178389 | 0.87 | KDM4E (0.35) | KDM4EL3MBTL1HPGDHSD17B10MAPT | |
| SCHEMBL18178109 | 0.87 | L3MBTL1 (0.41) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18178124 | 0.86 | PTGER1 (0.42) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18178107 | 0.86 | KDM4E (0.43) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 | |
| SCHEMBL18178119 | 0.86 | MRGPRX4 (0.49) | KDM4EL3MBTL1PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | KDM4E 2107/4885L3MBTL1 401/4885PTGER1 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.