Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | GUCY1B2 | O75343 | 2/20 | 0.35 |
| ▸ | GUCY1A2 | P33402 | 2/20 | 0.35 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.35 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178541 | 0.94 | MRGPRX4 (0.42) | SLC22A12MRGPRX4ACHEACLYKDM4E | |
| SCHEMBL18178706 | 0.93 | MRGPRX4 (0.40) | SLC22A12MRGPRX4ACHEACLYALDH1A1 | |
| SCHEMBL18182884 | 0.92 | SLC22A12 (0.39) | SLC22A12MRGPRX4ACHEACLYKDM4E | |
| SCHEMBL18178640 | 0.91 | SLC22A12 (0.39) | SLC22A12MRGPRX4ACHEALDH1A1SGMS2 | |
| SCHEMBL18178718 | 0.90 | MRGPRX4 (0.39) | SLC22A12MRGPRX4ACHEACLYKDM4E | |
| SCHEMBL18178746 | 0.90 | PTGS1 (0.39) | SLC22A12MRGPRX4ACHEACLYKDM4E | |
| SCHEMBL18183007 | 0.89 | SLC22A12 (0.39) | SLC22A12MRGPRX4ACHEACLYKDM4E | |
| SCHEMBL18178741 | 0.89 | MRGPRX4 (0.38) | SLC22A12MRGPRX4ACHEACLYKDM4E | |
| SCHEMBL18178693 | 0.89 | MRGPRX4 (0.38) | SLC22A12MRGPRX4ACHEACLYKDM4E | |
| SCHEMBL18178716 | 0.89 | ALDH1A1 (0.40) | MRGPRX4ACHEALDH1A1SGMS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | SLC22A12 4500/4885MRGPRX4 167/4885ACHE 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.