Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178848 | 0.89 | MRGPRX4 (0.43) | MRGPRX4L3MBTL1HSP90AA1UBE2NFFAR4 | |
| SCHEMBL18178966 | 0.88 | ALDH1A1 (0.38) | MRGPRX4RAB9AMAPTALDH1A1GAA | |
| SCHEMBL18182888 | 0.88 | FFAR4 (0.40) | MRGPRX4L3MBTL1FFAR1FFAR4ALDH1A1 | |
| SCHEMBL18178814 | 0.87 | MRGPRX4 (0.42) | MRGPRX4L3MBTL1HSP90AA1UBE2NPTGER1 | |
| SCHEMBL18178889 | 0.87 | MRGPRX4 (0.43) | MRGPRX4L3MBTL1HSP90AA1UBE2NPTGER1 | |
| SCHEMBL18178839 | 0.86 | MRGPRX4 (0.46) | MRGPRX4L3MBTL1HSP90AA1UBE2NPTGER1 | |
| SCHEMBL18178857 | 0.86 | MRGPRX4 (0.41) | MRGPRX4L3MBTL1HSP90AA1UBE2NFFAR4 | |
| SCHEMBL18178850 | 0.86 | MRGPRX4 (0.41) | MRGPRX4L3MBTL1HSP90AA1UBE2NFFAR4 | |
| SCHEMBL18178849 | 0.86 | MRGPRX4 (0.41) | MRGPRX4L3MBTL1HSP90AA1UBE2NFFAR4 | |
| SCHEMBL18178851 | 0.86 | MRGPRX4 (0.41) | MRGPRX4L3MBTL1HSP90AA1UBE2NFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | MRGPRX4 167/4885L3MBTL1 401/4885HSP90AA1 2605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.