Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178972 | 0.89 | MAPT (0.36) | MAPTRAB9ANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL18178975 | 0.89 | MAPT (0.39) | MAPTRAB9ANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL18178855 | 0.89 | MRGPRX4 (0.40) | MAPTRAB9AALDH1A1CYP1A2LMNA | |
| SCHEMBL18178943 | 0.87 | MAPT (0.36) | MAPTRAB9ANPSR1ALDH1A1SLC22A12 | |
| SCHEMBL18179022 | 0.87 | NPSR1 (0.35) | MAPTRAB9ANPSR1ALDH1A1SLC22A12 | |
| SCHEMBL18178974 | 0.87 | SLC22A12 (0.40) | MAPTRAB9ANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL18178969 | 0.86 | MAPT (0.40) | MAPTRAB9ANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL18179039 | 0.85 | NPSR1 (0.34) | MAPTRAB9ANPSR1ALDH1A1SLC22A12 | |
| SCHEMBL18182860 | 0.84 | ALDH1A1 (0.36) | MAPTRAB9ANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL18178978 | 0.83 | MAPT (0.37) | MAPTRAB9ANPSR1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | MAPT 4572/4885RAB9A 1136/4885NPSR1 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.