Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | DRD4 | P21917 | 6/20 | 0.52 |
| ▸ | DRD3 | P35462 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.49 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391255 | 1.00 | PPARA (0.52) | PPARAPPARDDRD2DRD4DRD3 | |
| SCHEMBL17879709 | 0.90 | CYP2C9 (0.51) | PPARAPPARDDRD2DRD4DRD3 | |
| SCHEMBL21889575 | 0.90 | CYP2C9 (0.51) | PPARAPPARDDRD2DRD4DRD3 | |
| SCHEMBL31542562 | 0.90 | DRD2 (0.52) | PPARAPPARDDRD2DRD4DRD3 | |
| SCHEMBL18405978 | 0.90 | DRD2 (0.52) | PPARAPPARDDRD2DRD4DRD3 | |
| SCHEMBL313373 | 0.86 | DRD2 (0.64) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| SCHEMBL31542566 | 0.85 | NR5A1 (0.56) | DRD2DRD4DRD3NPC1MAPT | |
| SCHEMBL31542570 | 0.85 | NR5A1 (0.56) | DRD2DRD4DRD3NPC1MAPT | |
| SCHEMBL31542559 | 0.85 | NR5A1 (0.56) | DRD2DRD4DRD3NPC1MAPT | |
| SCHEMBL18405940 | 0.85 | NR5A1 (0.56) | DRD2DRD4DRD3NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310913-A1 | FLEXIBLE TWO-DIMENSIONAL SINGLE-LAYER SUPRAMOLECUALR POLYMER TOWARD PRECISE NANO-SIZE SEPARATION | WU LIXIN (CN) | 2016-10-27 | — | — | US | disclosed |