Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21992378 | 0.95 | SYK (0.31) | PDE10A | |
| SCHEMBL19969220 | 0.91 | PDE10A (0.34) | PDE10A | |
| SCHEMBL21992753 | 0.90 | SYK (0.32) | PDE10A | |
| SCHEMBL21992362 | 0.89 | — | — | |
| SCHEMBL18181433 | 0.88 | HDAC4 (0.33) | PDE10A | |
| SCHEMBL21992380 | 0.88 | SYK (0.31) | PDE10A | |
| SCHEMBL21992731 | 0.88 | ADORA2A (0.33) | — | |
| SCHEMBL21992751 | 0.88 | BACE1 (0.32) | — | |
| SCHEMBL18181115 | 0.87 | PDE10A (0.33) | PDE10A | |
| SCHEMBL21992743 | 0.87 | PYGL (0.33) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016172425-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE (NO.5) LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |