Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180874 | 0.99 | — | — | |
| SCHEMBL10307511 | 0.82 | MAPK1 (0.42) | MAPK1LMNACYP1A2 | |
| SCHEMBL30174115 | 0.82 | MAPK1 (0.42) | MAPK1LMNACYP1A2 | |
| SCHEMBL18180881 | 0.74 | MAPK1 (0.30) | MAPK1LMNACYP1A2 | |
| SCHEMBL18180875 | 0.70 | PTGIR (0.31) | — | |
| Grossheimin SCHEMBL1711489 | 0.70 | MAPT (0.34) | MAPK1 | |
| Grossheimin SCHEMBL1711493 | 0.70 | MAPT (0.34) | MAPK1 | |
| SCHEMBL10307515 | 0.65 | — | — | |
| SCHEMBL22877988 | 0.63 | MAPK1 (0.41) | MAPK1LMNACYP1A2 | |
| SCHEMBL12459727 | 0.63 | MAPK1 (0.41) | MAPK1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016169573-A1 | SESQUITERPENE LACTONES AS POTENT AND BROAD SPECTRUM ANTIVIRAL COMPOUNDS AGAINST ALL GENOTYPES OF HEPATITIS C VIRUS (HCV) | ELSEBAI MAHMOUD FAHMI (EG) | 2016-10-27 | — | — | WO | disclosed |