Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180912 | 0.81 | MEN1 (0.33) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18180918 | 0.81 | MEN1 (0.33) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18180919 | 0.73 | MEN1 (0.34) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18180915 | 0.65 | MEN1 (0.32) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18180929 | 0.64 | — | — | |
| SCHEMBL10307515 | 0.61 | — | — | |
| SCHEMBL13822287 | 0.61 | CYP3A4 (0.31) | — | |
| SCHEMBL18180928 | 0.60 | — | — | |
| SCHEMBL10307520 | 0.54 | MAPT (0.35) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18180889 | 0.54 | MAPT (0.35) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016169573-A1 | SESQUITERPENE LACTONES AS POTENT AND BROAD SPECTRUM ANTIVIRAL COMPOUNDS AGAINST ALL GENOTYPES OF HEPATITIS C VIRUS (HCV) | ELSEBAI MAHMOUD FAHMI (EG) | 2016-10-27 | — | — | WO | disclosed |