Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18181950 | 0.90 | MRGPRX4 (0.41) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL18182836 | 0.90 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL18182999 | 0.90 | CYP1A2 (0.46) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL18156244 | 0.89 | ALOX15 (0.40) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL18181996 | 0.89 | MRGPRX4 (0.44) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL18182011 | 0.88 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL18156409 | 0.88 | SLC22A12 (0.44) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL18182036 | 0.88 | MRGPRX4 (0.44) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL18178456 | 0.88 | MRGPRX4 (0.49) | NPC1RAB9ASMN1; SMN2MAPTMRGPRX4 | |
| SCHEMBL18156399 | 0.88 | FFAR4 (0.47) | MAPTMRGPRX4ALOX15CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | NPC1 1520/4885RAB9A 1136/4885SMN1; SMN2 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.