Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.57 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18183160 | 0.89 | KDM1A (0.61) | KDM1AUSP30GPR119 | |
| SCHEMBL18173263 | 0.85 | KDM1A (0.66) | KDM1A | |
| SCHEMBL18173265 | 0.85 | KDM1A (0.66) | KDM1A | |
| SCHEMBL18182633 | 0.80 | KDM1A (0.73) | KDM1A | |
| SCHEMBL18182597 | 0.80 | KDM1A (0.73) | KDM1A | |
| SCHEMBL18182985 | 0.80 | KDM1A (0.73) | KDM1A | |
| SCHEMBL18183147 | 0.80 | KDM1A (0.73) | KDM1A | |
| SCHEMBL18182141 | 0.80 | KDM1A (0.73) | KDM1A | |
| SCHEMBL18173453 | 0.80 | KDM1A (0.47) | KDM1ANAMPTGPR119 | |
| SCHEMBL18173454 | 0.80 | KDM1A (0.47) | KDM1ANAMPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |
| WO-2016172496-A1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-10-27 | — | — | WO | disclosed |