Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18203768 | 0.89 | HSD17B1 (0.67) | HSD17B1HSD17B2 | |
| SCHEMBL18186443 | 0.81 | HSD17B1 (0.75) | HSD17B1HSD17B2 | |
| SCHEMBL18186604 | 0.80 | HSD17B1 (0.80) | HSD17B1HSD17B2 | |
| SCHEMBL18186459 | 0.80 | HSD17B1 (0.79) | HSD17B1HSD17B2 | |
| SCHEMBL18186460 | 0.74 | HSD17B1 (0.69) | HSD17B1HSD17B2 | |
| SCHEMBL18186543 | 0.70 | HSD17B1 (0.66) | HSD17B1HSD17B2 | |
| SCHEMBL18186494 | 0.70 | HSD17B1 (0.68) | HSD17B1HSD17B2 | |
| SCHEMBL18186448 | 0.68 | HSD17B1 (1.00) | HSD17B1HSD17B2 | |
| SCHEMBL18186464 | 0.68 | HSD17B1 (0.42) | HSD17B1HSD17B2 | |
| SCHEMBL18186432 | 0.67 | HSD17B1 (1.00) | HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884839-B2 | Inhibitors of 17Beta-hydroxysteroid dehydrogenases type 1 and type 2 | ELEXOPHARM GMBH (DE) | 2018-02-06 | — | — | US | disclosed |
| US-20160318895-A1 | Inhibitors of 17Beta-Hydroxysteroid Dehydrogenases Type 1 and Type 2 | ELEXOPHARM GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318895-A1 | Inhibitors of 17Beta-Hydroxysteroid Dehydrogenases Type 1 and Type 2 | HSD17B1, HSD17B2, HSD17B3 | HSD17B1 1/4885HSD17B2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.