Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824801 | 0.85 | MCL1 (0.43) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL1822178 | 0.84 | NPSR1 (0.47) | NPSR1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1821302 | 0.82 | NPSR1 (0.52) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1820714 | 0.81 | HDAC8 (0.43) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL1817638 | 0.75 | KMT2A (0.52) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1818670 | 0.72 | MCL1 (0.40) | MEN1KMT2ATBXA2RFBP1MAPT | |
| SCHEMBL29931026 | 0.69 | NPSR1 (0.58) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1695081 | 0.69 | NPSR1 (0.58) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1823517 | 0.69 | MAPT (0.40) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL1820711 | 0.68 | MCL1 (0.43) | MEN1KMT2AMAPTALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947712-B2 | Antiarthritic agents; asthma; chronic obstructive pulminary diosrders; atherosclerosis; vision defects; hepatitis; central nervous system disorders; cardiovascular disorders; wound healing agents; restenosis; cirrhosis; multiple sclerosis; glomerulonephritis; graft versus host disease; antidiabetic agent | WYETH LLC (US) | 2011-05-24 | — | — | US | disclosed |