SCHEMBL18187

SCHEMBL18187

CC1CC(C)(C)CC(c2ccc(O)cc2)(c2ccc(O)cc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 7/20 1.00
ESR1 P03372 5/20 1.00
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPT P10636 2/20 0.32
NPY1R P25929 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALOX12 P18054 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
HPGD P15428 1/20 0.31
RECQL P46063 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21291805 1.00 ESR2 (1.00) ESR2ESR1MMP2MMP9CYP3A4
SCHEMBL4826617 1.00 ESR2 (1.00) ESR2ESR1MMP2MMP9CYP3A4
Bicarbonate SCHEMBL3892407 0.94 ESR1 (0.88) ESR2ESR1MMP2MMP9CYP3A4
SCHEMBL21624439 0.94 ESR1 (0.88) ESR2ESR1CYP3A4CYP2D6TSHR
Phenol SCHEMBL7804481 0.94 ESR2 (0.88) ESR2ESR1CYP3A4CYP2D6TSHR
SCHEMBL19751234 0.94 ESR1 (0.88) ESR2ESR1CYP3A4CYP2D6TSHR
Phenol SCHEMBL1982817 0.94 ESR2 (0.88) ESR2ESR1CYP3A4CYP2D6TSHR
SCHEMBL822979 0.94 ESR2 (0.88) ESR2ESR1MMP2MMP9MAPT
SCHEMBL21624438 0.91 ESR2 (0.82) ESR2ESR1ALDH1A1KDM4EALOX12
Bisphenol A SCHEMBL8606541 0.91 ESR2 (0.82) ESR2ESR1CYP3A4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13195 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747302-A2 REPAIR AND OPTIMIZATION OF NANOCOMPOSITE MATERIALS Nanocore ApS (DK) 2026-05-27 EP claimed
CN-119192554-B Copolycarbonate resin and preparation method and application thereof 万华化学集团股份有限公司 2026-05-19 CN claimed
EP-4720052-A1 CHROMOPHORE-FUNCTIONAL POLYOLS ARKEMA France (FR) 2026-04-08 EP claimed
EP-3822299-B1 BIO-BASED POLYCARBONATE ESTER RESIN FOR EYEGLASS FRAME SK CHEMICALS CO LTD (KR) 2026-02-18 EP claimed
EP-4688229-A1 NANOPOROUS POLYMER MATERIALS AND A FACILE PROCESS FOR THEIR PREPARATION Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-02-11 EP claimed
US-12545756-B2 Curable resin composition, molded article and method for producing same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-02-10 US claimed
US-12540218-B2 Polycarbonate/polyorganosiloxane copolymer and resin composition including said copolymer IDEMITSU KOSAN CO., LTD. (JP) 2026-02-03 US claimed
US-20260015499-A1 POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2026-01-15 US claimed
WO-2025242591-A1 METHOD FOR THE EFFICIENT ENZYMATIC DEGRADATION OF AROMATIC POLYCARBONATES COVESTRO DEUTSCHLAND AG (DE) 2025-11-27 WO claimed
EP-4642853-A1 POLYCARBONATE COMPOSITION Covestro Deutschland AG (DE) 2025-11-05 EP claimed
US-5104959-A POLYURETHANE-BASED REACTIVE ADHESIVES IN WHICH THE ISOCYANATE IS STABILIZED BY A POLYETHER AMINE BAYER AKTIENGESELLSCHAFT (DE) 1992-04-14 US claimed
EP-0359953-B1 DIHYDROXYDIPHENYLCYCLOALKANES, THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF HIGH MOLECULAR POLYCARBONATES BAYER AG (DE) 1992-01-22 EP claimed
EP-0457103-A1 Mixtures of polyamides with aromatic (co)poly(ester)-carbonates based on tertiary alkyl ester groups containing bisphenols BAYER AG (DE) 1991-11-21 EP claimed
EP-0439732-A2 Polyamide mouldings BAYER AG (DE) 1991-08-07 EP claimed
EP-0436186-A2 Thermostable polycarbonate moulding compositions having dimensional stability under heat and improved processability BAYER AG (DE) 1991-07-10 EP claimed
EP-0432596-A2 Thermoplastic polyurethane with improved fluidity BAYER AG (DE) 1991-06-19 EP claimed
EP-0425860-A2 Polyamide moulding compositions containing bisphenoles with high glass transition temperature BAYER AG (DE) 1991-05-08 EP claimed
EP-0423564-A2 Process for the preparation of prepregs/composites BAYER AG (DE) 1991-04-24 EP claimed
US-4982014-A Dihydroxydiphenyl cycloalkanes, their production and their use for the production of high molecular weight polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1991-01-01 US claimed
EP-0402726-A1 Reactive adhesives based on polyurethane BAYER AG (DE) 1990-12-19 EP claimed