SCHEMBL822979

SCHEMBL822979

Cc1ccc(C2(c3ccc(O)cc3)CC(C)CC(C)(C)C2)cc1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.88
ESR1 P03372 3/20 0.88
ACHE P22303 1/20 0.41
CCR2 P41597 1/20 0.38
MAOB P27338 4/20 0.35
MAOA P21397 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A3 Q01959 2/20 0.35
CHRNA1 P02708 1/20 0.35
CHRNG P07510 1/20 0.35
CHRNB1 P11230 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
CHRND Q07001 1/20 0.35
NR3C1 P04150 1/20 0.34
MGAT2 Q10469 1/20 0.32
SLC6A4 P31645 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21291805 0.94 ESR2 (1.00) ESR2ESR1MAPTMMP2MMP9
SCHEMBL4826617 0.94 ESR2 (1.00) ESR2ESR1MAPTMMP2MMP9
SCHEMBL18187 0.94 ESR2 (1.00) ESR2ESR1MAPTMMP2MMP9
SCHEMBL19200619 0.92 ESR1 (0.72) ESR2ESR1CCR2MAOBMAOA
SCHEMBL19751234 0.88 ESR1 (0.88) ESR2ESR1CCR2MAPT
SCHEMBL21624439 0.88 ESR1 (0.88) ESR2ESR1CCR2MAPT
Bicarbonate SCHEMBL3892407 0.88 ESR1 (0.88) ESR2ESR1CCR2MAPTMMP2
Phenol SCHEMBL1982817 0.88 ESR2 (0.88) ESR2ESR1CCR2MAPT
Phenol SCHEMBL7804481 0.88 ESR2 (0.88) ESR2ESR1CCR2MAPT
SCHEMBL21624438 0.85 ESR2 (0.82) ESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209206-A1 Flame Retardant Polycarbonate Composition With High Comparative Tracking Index COVESTRO DEUTSCHLAND AG (DE) 2024-06-27 US disclosed
US-20230174700-A1 CURABLE RESIN COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-06-08 US disclosed
US-20230174700-A1 CURABLE RESIN COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-06-08 US disclosed
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2018-08-02 US disclosed
US-9902706-B2 Process for making benzoxazines CYTEC INDUSTRIES INC. (US) 2018-02-27 US disclosed
US-20170369679-A1 NOR-HALS COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2017-12-28 US disclosed
US-9771458-B2 Reactive functional siloxane compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2017-09-26 US disclosed
US-9745424-B2 Insoluble and branched polyphosphonates and methods related thereto FRX POLYMERS, INC. (US) 2017-08-29 US disclosed
US-9715040-B2 Optical film and manufacturing method thereof, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-20170190907-A1 HIGH FLOW, HIGH HEAT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-06 US disclosed
US-20110294920-A1 DOPO-FLAME RETARDANT IN EPOXY RESINS BASF SE (DE) 2011-12-01 US disclosed
US-20110288206-A1 MELAMINE PHENYLPHOSPHINATE FLAME RETARDANT COMPOSITIONS BASF SE (DE) 2011-11-24 US disclosed
US-20110266507-A1 MELAMINE PHENYLPHOSPHONATE FLAME RETARDANT COMPOSITIONS BASF SE (DE) 2011-11-03 US disclosed
US-20110237715-A1 FLAME RETARDANT COMPOSITIONS OF PHOSPHINIC ACID SALTS AND NITROXYL DERIVATIVES BASF SE (DE) 2011-09-29 US disclosed
US-20110190428-A1 FLAME RETARDANT COMPOSITIONS WITH POLYMERIC DISPERSING AGENTS BASF SE (DE) 2011-08-04 US disclosed
US-7649073-B2 Polycarbonate-poly(alkylene oxide) copolymer compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-19 US disclosed
US-7563505-B2 Long-time stable water-repellent and oil-repellent surface SUNYX SURFACE NANOTECHNOLOGIES GMBH (DE) 2009-07-21 US disclosed
US-20090032770-A1 Insoluble and Branched Polyphosphonates and Methods Related Thereto FRX POLYMERS, LLC (US) 2009-02-05 US disclosed
US-20080312374-A1 POLYCARBONATE-POLY(ALKYLENE OXIDE) COPOLYMER COMPOSITIONS AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-12-18 US disclosed
WO-2007081593-A1 THERMALLY STABLE POLYCARBONATES, THERMOPLASTIC COMPOSITIONS THEREOF, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288206-A1 MELAMINE PHENYLPHOSPHINATE FLAME RETARDANT COMPOSITIONS PHOSPHO1, FLAD1, PFAS ESR2 871/4885ESR1 1985/4885ACHE 2619/4885
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS PFAS, PCBP1, DDT ESR2 2354/4885ESR1 2299/4885ACHE 3300/4885
US-20170369679-A1 NOR-HALS COMPOUNDS AS FLAME RETARDANTS PFAS, NONO, PARG ESR2 3543/4885ESR1 4170/4885ACHE 3229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.