Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213031 | 0.75 | — | — | |
| SCHEMBL3249818 | 0.75 | EBP (0.39) | — | |
| SCHEMBL759276 | 0.73 | — | — | |
| SCHEMBL181760 | 0.72 | BRD4 (0.31) | — | |
| SCHEMBL3263298 | 0.72 | KMT2A (0.32) | — | |
| SCHEMBL182227 | 0.71 | ITGB2 (0.43) | — | |
| SCHEMBL266615 | 0.70 | NISCH (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL12401665 | 0.70 | NISCH (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL8347684 | 0.70 | NISCH (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL3470534 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979916-B1 | CHEMICAL DEFUNCTIONALIZATION OF POLYMERIC ALKYLENEDIOXYHETEROCYCLICS | UNIV FLORIDA (US) | 2012-03-21 | — | — | EP | claimed |
| US-7807758-B2 | Chemical defunctionalization of polymeric alkylenedioxyheterocyclics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-10-05 | — | — | US | claimed |
| US-20090221763-A1 | Chemical Defunctionalization of Polymeric Alkylenedioxyheterocyclics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-09-03 | — | — | US | claimed |
| EP-1979916-A2 | CHEMICAL DEFUNCTIONALIZATION OF POLYMERIC ALKYLENEDIOXYHETEROCYCLICS | University of Florida Research Foundation, Incorporated (US) | 2008-10-15 | — | — | EP | claimed |
| WO-2007087587-A2 | CHEMICAL DEFUNCTIONALIZATION OF POLYMERIC ALKYLENEDIOXYHETEROCYCLICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2007-08-02 | — | — | WO | claimed |
| EP-2402955-B1 | Chemical defunctionalization of polymeric alkylenedioxyheterocyclics - the monomers | UNIV FLORIDA (US) | 2013-07-03 | — | — | EP | disclosed |
| EP-1979916-B1 | CHEMICAL DEFUNCTIONALIZATION OF POLYMERIC ALKYLENEDIOXYHETEROCYCLICS | UNIV FLORIDA (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2402955-A1 | Chemical defunctionalization of polymeric alkylenedioxyheterocyclics - the monomers | University of Florida Research Foundation, Incorporated (US) | 2012-01-04 | — | — | EP | disclosed |
| US-7807758-B2 | Chemical defunctionalization of polymeric alkylenedioxyheterocyclics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090221763-A1 | Chemical Defunctionalization of Polymeric Alkylenedioxyheterocyclics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1979916-A2 | CHEMICAL DEFUNCTIONALIZATION OF POLYMERIC ALKYLENEDIOXYHETEROCYCLICS | University of Florida Research Foundation, Incorporated (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007087587-A2 | CHEMICAL DEFUNCTIONALIZATION OF POLYMERIC ALKYLENEDIOXYHETEROCYCLICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221763-A1 | Chemical Defunctionalization of Polymeric Alkylenedioxyheterocyclics | DDT, STAT3, PTPN22 | CHRNB4 3665/4885CHRNA3 2826/4885CHRNB2 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.