Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Iodobenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodobenzene SCHEMBL10616506 | 1.00 | — | — | |
| Iodobenzene SCHEMBL1587 | 0.96 | — | — | |
| Iodobenzene SCHEMBL10538620 | 0.96 | ALDH1A1 (0.43) | — | |
| Iodobenzene SCHEMBL10481785 | 0.96 | ALDH1A1 (0.43) | — | |
| Iodobenzene SCHEMBL3628957 | 0.96 | — | — | |
| Iodobenzene SCHEMBL1331855 | 0.96 | — | — | |
| Iodobenzene SCHEMBL10878191 | 0.92 | — | — | |
| Iodobenzene SCHEMBL2250668 | 0.92 | — | — | |
| Iodobenzene SCHEMBL4335131 | 0.92 | ALDH1A1 (0.40) | — | |
| Iodobenzene SCHEMBL20608266 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3741392-A1 | POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING DIAGNOSIS AND PHOTODYNAMIC THERAPY, AND PREPARATION METHOD THEREFOR | Seoul National University R & DB Foundation (KR) | 2020-11-25 | — | — | EP | claimed |
| CN-111954543-A | Positron emission tomography radioactive tracer for translocator overexpression related diseases, translocator targeting ligand for fluorescence imaging diagnosis and photodynamic therapy and preparation method thereof | 首尔国立大学校产学协力财团 | 2020-11-17 | — | — | CN | claimed |
| US-20200345870-A1 | POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2020-11-05 | — | — | US | claimed |
| US-20260061083-A1 | POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATGON (KR) | 2026-03-05 | — | — | US | disclosed |
| US-12491271-B2 | Positron emission tomography radiotracer for diseases associated with translocator protein overexpression, translocator protein-targeting ligand for fluorescence imaging-guided surgery and photodynamic therapy, and production methods therefor | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2025-12-09 | — | — | US | disclosed |
| EP-3288735-B1 | PROCESS FOR HALOGENATING OLEFINIC-DERIVED ELASTOMERS IN THE BULK PHASE | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-07-03 | — | — | EP | disclosed |
| US-20240156997-A1 | POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2024-05-16 | — | — | US | disclosed |
| US-20220371253-A1 | System and Process for Halogenating Olefinic-Derived Elastomers in the Bulk Phase | EXXONMOBILE CHEMICAL PATENTS INC (US) | 2022-11-24 | — | — | US | disclosed |
| US-10947375-B2 | System and process for the production of functionalized olefinic-based polymer | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-03-16 | — | — | US | disclosed |
| EP-3408019-B1 | SYSTEM AND PROCESS FOR THE PRODUCTION OF FUNCTIONALIZED OLEFINIC-BASED POLYMER | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2021-01-20 | — | — | EP | disclosed |
| EP-3741392-A1 | POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING DIAGNOSIS AND PHOTODYNAMIC THERAPY, AND PREPARATION METHOD THEREFOR | Seoul National University R & DB Foundation (KR) | 2020-11-25 | — | — | EP | disclosed |
| US-20200345870-A1 | POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2020-11-05 | — | — | US | disclosed |
| US-20200255643-A1 | System and Process for the Production of Functionalized Olefinic-Based Polymer | EXXONMOBIL CHEMICAL PATENTS INC. | 2020-08-13 | — | — | US | disclosed |
| CN-107548343-B | System and process for halogenating olefin-derived elastomers in bulk phase | 埃克森美孚化学专利公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-108472618-B | Systems and methods for producing functionalized olefin-based polymers | 埃克森美孚化学专利公司 | 2020-04-28 | — | — | CN | disclosed |
| EP-3408019-A1 | SYSTEM AND PROCESS FOR THE PRODUCTION OF FUNCTIONALIZED OLEFINIC-BASED POLYMER | ExxonMobil Chemical Patents Inc. (US) | 2018-12-05 | — | — | EP | disclosed |
| US-20180085989-A1 | System and Process for Halogenating Olefinic-Derived Elastomers in the Bulk Phase | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-03-29 | — | — | US | disclosed |
| EP-3288735-A1 | SYSTEM AND PROCESS FOR HALOGENATING OLEFINIC-DERIVED ELASTOMERS IN THE BULK PHASE | ExxonMobil Chemical Patents Inc. (US) | 2018-03-07 | — | — | EP | disclosed |
| WO-2017131869-A1 | SYSTEM AND PROCESS FOR THE PRODUCTION OF FUNCTIONALIZED OLEFINIC-BASED POLYMER | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-08-03 | — | — | WO | disclosed |
| WO-2016175938-A1 | SYSTEM AND PROCESS FOR HALOGENATING OLEFINIC-DERIVED ELASTOMERS IN THE BULK PHASE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-11-03 | — | — | WO | disclosed |