Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21538566 | 1.00 | FOLH1 (0.51) | FOLH1SMN1; SMN2KMT2ACA2CA1 | |
| SCHEMBL6700916 | 0.87 | FOLH1 (0.61) | FOLH1SMN1; SMN2RIMKLANAALAD2 | |
| Hydrochloric Acid SCHEMBL28220853 | 0.83 | FOLH1 (0.46) | FOLH1SMN1; SMN2KMT2ACA2CA1 | |
| SCHEMBL27623042 | 0.82 | FOLH1 (0.50) | FOLH1KMT2ACA2CA1RIMKLA | |
| SCHEMBL25267184 | 0.81 | SMN1; SMN2 (0.46) | FOLH1SMN1; SMN2 | |
| SCHEMBL31444322 | 0.81 | SMN1; SMN2 (0.46) | FOLH1SMN1; SMN2 | |
| SCHEMBL12986944 | 0.81 | KMT2A (0.44) | FOLH1KMT2ACA2CA1RIMKLA | |
| SCHEMBL8088657 | 0.80 | SMN1; SMN2 (0.49) | FOLH1SMN1; SMN2KMT2A | |
| SCHEMBL21324906 | 0.80 | FOLH1 (0.51) | FOLH1SMN1; SMN2CA2CA1 | |
| SCHEMBL16557162 | 0.80 | FOLH1 (0.51) | FOLH1SMN1; SMN2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |