Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RUNX1 | Q01196 | 6/20 | 0.43 |
| ▸ | CBFB | Q13951 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190875 | 0.87 | RUNX1 (0.56) | RUNX1CBFBTRPV1KIF11GAA | |
| SCHEMBL1193332 | 0.81 | RUNX1 (0.43) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL7066940 | 0.81 | RUNX1 (0.43) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL9674984 | 0.81 | NPSR1 (0.53) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL2108293 | 0.81 | RUNX1 (0.43) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL5683128 | 0.81 | NPC1 (0.48) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL11903454 | 0.81 | KDM4E (0.47) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL23676457 | 0.80 | SCN10A (0.56) | RUNX1CBFBTRPV1KIF11KDM4E | |
| Hydrochloric Acid SCHEMBL9765811 | 0.79 | NPC1 (0.49) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL18659785 | 0.78 | TRPV1 (0.50) | RUNX1CBFBTRPV1KIF11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |