Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RUNX1 | Q01196 | 6/20 | 0.43 |
| ▸ | CBFB | Q13951 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674984 | 0.81 | NPSR1 (0.53) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL11903454 | 0.81 | KDM4E (0.47) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL2108293 | 0.81 | RUNX1 (0.43) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL5683128 | 0.81 | NPC1 (0.48) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL1193332 | 0.81 | RUNX1 (0.43) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL18190876 | 0.81 | RUNX1 (0.43) | RUNX1CBFBTRPV1KIF11KDM4E | |
| Hydrochloric Acid SCHEMBL9765811 | 0.79 | NPC1 (0.49) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL30109002 | 0.78 | RUNX1 (0.41) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL20320804 | 0.78 | RUNX1 (0.41) | RUNX1CBFBTRPV1KIF11KDM4E | |
| SCHEMBL18659785 | 0.78 | TRPV1 (0.50) | RUNX1CBFBTRPV1KIF11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844998-B1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-20030027842-A1 | Halogenobenzimidazoles | ASSMANN LUTZ (DE) | 2003-02-06 | — | — | US | disclosed |
| US-6387939-B1 | PLANT SAFENING AGNETS; FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-14 | — | — | US | disclosed |
| US-6268508-B1 | FOR CROP PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-31 | — | — | US | disclosed |
| US-6160001-A | Halobenzimidazoles and their use as microbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| US-6127547-A | FOR CROP PROTECTION; SUCH AS 2-BROMO-6,6-DIFLUORO(1,3)DIOXOLO(4,5-F)BENZIMIDAZOLE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-6020354-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |
| EP-0844998-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997006171-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027842-A1 | Halogenobenzimidazoles | MSR1, MRPS23, CBR1 | RUNX1 1179/4885CBFB 1508/4885TRPV1 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.