Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18192079 | 0.87 | KCNJ1 (0.35) | KCNJ1KCNH2 | |
| SCHEMBL18192073 | 0.85 | KCNJ1 (0.32) | KCNJ1KCNH2 | |
| SCHEMBL18192064 | 0.83 | KCNJ1 (0.37) | KCNJ1KCNH2 | |
| SCHEMBL18192057 | 0.83 | KCNJ1 (0.33) | KCNJ1KCNH2 | |
| SCHEMBL15437506 | 0.78 | KCNJ1 (0.50) | KCNJ1KCNH2 | |
| SCHEMBL18204185 | 0.73 | USP2 (0.36) | KCNJ1 | |
| SCHEMBL18192074 | 0.72 | KCNJ1 (0.35) | KCNJ1KCNH2 | |
| SCHEMBL16096100 | 0.70 | HRH3 (0.48) | KCNJ1 | |
| SCHEMBL18192075 | 0.70 | KCNJ1 (0.35) | KCNJ1KCNH2 | |
| SCHEMBL17760272 | 0.68 | KCNJ1 (0.40) | KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877471-B1 | SPIRO-FUSED PIPERIDINE DERIVATIVES FOR USE AS INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2016-11-02 | — | — | EP | disclosed |