Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15465508 | 1.00 | ALDH1A1 (0.32) | ALDH1A1PDE2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15465123 | 1.00 | ALDH1A1 (0.32) | ALDH1A1PDE2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15464699 | 1.00 | ALDH1A1 (0.32) | ALDH1A1PDE2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15465168 | 0.97 | ALDH1A1 (0.32) | ALDH1A1PDE2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18192145 | 0.97 | ALDH1A1 (0.32) | ALDH1A1PDE2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15464942 | 0.97 | ALDH1A1 (0.32) | ALDH1A1PDE2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17454964 | 0.83 | ALDH1A1 (0.30) | ALDH1A1PDE2A | |
| SCHEMBL20485796 | 0.81 | AKT1 (0.34) | ALDH1A1PDE2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20485804 | 0.81 | AKT1 (0.34) | ALDH1A1PDE2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16290213 | 0.79 | SCN9A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2974730-B1 | DRUG FOR RESPIRATORY DISEASES | DAIICHI SANKYO CO LTD (JP) | 2018-01-31 | — | — | EP | disclosed |
| EP-2813491-B1 | CYCLOALKANE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2016-11-02 | — | — | EP | disclosed |