Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 1.00 |
| ▸ | MTOR | P42345 | 2/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.57 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311669 | 0.91 | PIK3CA (0.82) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL1309740 | 0.88 | PIK3CA (0.78) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL12499681 | 0.85 | PIK3CA (0.73) | PIK3CAMTORPIK3CGPIK3R1HRH4 | |
| SCHEMBL15386510 | 0.85 | HRH4 (0.75) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL908397 | 0.84 | PIK3CA (0.72) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL15386499 | 0.81 | PIK3CA (0.69) | PIK3CAMTORPIK3R1HRH4 | |
| SCHEMBL908873 | 0.81 | PIK3CA (0.67) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL14614250 | 0.80 | PIK3CA (0.69) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL1311825 | 0.80 | PIK3CA (0.66) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL1309606 | 0.80 | PIK3CA (0.68) | PIK3CAMTORPIK3CDPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481670-B2 | Triazine compounds | SPHAERA PHARMA PTE. LTD. (SG) | 2016-11-01 | — | — | US | disclosed |
| US-9481670-B2 | Triazine compounds | SPHAERA PHARMA PTE. LTD. (SG) | 2016-11-01 | — | — | US | disclosed |