Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224478 | 0.73 | HSD11B1 (0.42) | ASGR1HSD11B1CTSDCTSLCTSB | |
| SCHEMBL30097101 | 0.71 | ASGR1 (0.36) | ASGR1CTSDCTSLCTSBCTSS | |
| SCHEMBL28781534 | 0.71 | HSD11B1 (0.40) | ASGR1HSD11B1CTSDCTSLCTSB | |
| SCHEMBL28781536 | 0.71 | HSD11B1 (0.40) | ASGR1HSD11B1CTSDCTSLCTSB | |
| SCHEMBL29326213 | 0.71 | GAA (0.44) | HSD11B1GAA | |
| SCHEMBL190837 | 0.70 | HSD11B1 (0.47) | ASGR1HSD11B1 | |
| SCHEMBL10238605 | 0.69 | ASGR1 (0.35) | ASGR1HSD11B1CTSDCTSLCTSB | |
| SCHEMBL18696723 | 0.69 | ASGR1 (0.43) | ASGR1HSD11B1 | |
| SCHEMBL25279038 | 0.68 | ASGR1 (0.39) | ASGR1HSD11B1 | |
| SCHEMBL27849879 | 0.68 | HSD11B1 (0.40) | ASGR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217610-B1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN INC (US) | 2016-11-02 | — | — | EP | disclosed |