Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19338390 | 0.84 | MET (0.63) | MET | |
| SCHEMBL14346083 | 0.83 | MET (1.00) | MET | |
| SCHEMBL1163324 | 0.83 | MET (1.00) | MET | |
| SCHEMBL12049148 | 0.83 | MET (0.75) | MET | |
| SCHEMBL14346082 | 0.80 | MET (1.00) | MET | |
| SCHEMBL2699456 | 0.80 | MET (0.78) | MET | |
| SCHEMBL12049152 | 0.80 | MET (0.71) | MET | |
| SCHEMBL3590807 | 0.79 | MET (0.69) | MET | |
| SCHEMBL2494788 | 0.79 | MET (0.76) | MET | |
| SCHEMBL12049044 | 0.79 | MET (0.69) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966214-B9 | TRIAZOLOPYRIDAZINES AS TYROSINE KINASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-09-13 | — | — | EP | disclosed |
| EP-1966214-B1 | TRIAZOLOPYRIDAZINES AS TYROSINE KINASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-11-02 | — | — | EP | disclosed |