Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2499476 | 0.89 | MET (0.46) | MET | |
| SCHEMBL14439068 | 0.78 | MET (0.44) | MET | |
| SCHEMBL2493611 | 0.77 | MET (0.43) | MET | |
| SCHEMBL2491763 | 0.72 | MET (0.47) | MET | |
| SCHEMBL14465811 | 0.70 | MET (0.43) | MET | |
| SCHEMBL14439111 | 0.70 | MET (0.40) | MET | |
| SCHEMBL2495186 | 0.70 | MET (0.46) | MET | |
| SCHEMBL2493071 | 0.70 | MET (0.47) | MET | |
| SCHEMBL2497289 | 0.70 | MET (0.52) | MET | |
| SCHEMBL19338434 | 0.68 | HDAC1 (0.38) | METEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966214-B1 | TRIAZOLOPYRIDAZINES AS TYROSINE KINASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-11-02 | — | — | EP | disclosed |