SCHEMBL18199232

SCHEMBL18199232

C=CC(=O)OCCCCOC(=O)c1cc(O)c(C(=O)OCCCCOC(=O)C=C)cc1O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.58
ALDH1A1 P00352 3/20 0.58
CYP3A4 P08684 2/20 0.58
HPGD P15428 1/20 0.49
SERPINE1 P05121 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
TP53 P04637 3/20 0.44
HIF1A Q16665 2/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 1/20 0.41
MAPK1 P28482 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18199227 0.86 SERPINE1 (0.67) TSHRALDH1A1CYP3A4HPGDSERPINE1
SCHEMBL15425253 0.86 CA12 (0.55) TSHRALDH1A1CYP3A4HPGDSERPINE1
SCHEMBL4593811 0.85 CA12 (0.54) TSHRALDH1A1CYP3A4HPGDSERPINE1
SCHEMBL21524610 0.84 TSHR (0.42) TSHRALDH1A1CYP3A4HPGDSERPINE1
SCHEMBL11662346 0.84 TDP1 (0.51) TSHRALDH1A1CYP3A4HPGDSERPINE1
SCHEMBL12532972 0.83 SERPINE1 (0.67) TSHRALDH1A1CYP3A4HPGDSERPINE1
SCHEMBL7115632 0.81 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTDP1
SCHEMBL9767720 0.81 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTDP1
SCHEMBL8158959 0.80 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTDP1
SCHEMBL4892171 0.80 SERPINE1 (0.76) TSHRALDH1A1SERPINE1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457628-B2 Polymerizable compound, polymerizable composition, film, and half mirror for displaying projection image FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-20160318845-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, FILM, AND HALF MIRROR FOR DISPLAYING PROJECTION IMAGE FUJIFILM CORPORATION (JP) 2016-11-03 US disclosed
US-20160318845-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, FILM, AND HALF MIRROR FOR DISPLAYING PROJECTION IMAGE FUJIFILM CORPORATION (JP) 2016-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457628-B2 Polymerizable compound, polymerizable composition, film, and half mirror for displaying projection image PYM1, C5, C1S TSHR 3946/4885ALDH1A1 3142/4885CYP3A4 4473/4885
US-20160318845-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, FILM, AND HALF MIRROR FOR DISPLAYING PROJECTION IMAGE PYM1, C5, C1S TSHR 3939/4885ALDH1A1 3192/4885CYP3A4 4483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.