Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | SLC47A2 | Q86VL8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16386198 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AHRH2SLC22A2CA12 | |
| SCHEMBL10776417 | 0.79 | SLC22A2 (0.50) | SMN1; SMN2HRH2SLC22A2CA12SLC22A3 | |
| Hydrochloric Acid SCHEMBL8934520 | 0.78 | SLC22A2 (0.49) | SMN1; SMN2HRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL16386448 | 0.78 | SMN1; SMN2 (0.32) | SMN1; SMN2KMT2AHRH2SLC22A2CA12 | |
| SCHEMBL16386195 | 0.76 | HRH2 (0.36) | SMN1; SMN2KMT2AHRH2SLC22A2CA12 | |
| SCHEMBL16386449 | 0.73 | MAPT (0.38) | SMN1; SMN2HRH2SLC22A2CA12SLC22A3 | |
| Hydrochloric Acid SCHEMBL10960221 | 0.66 | KMT2A (0.59) | SMN1; SMN2KMT2ALMNAMAPTATP4A | |
| Hydrochloric Acid SCHEMBL10960212 | 0.66 | KMT2A (0.59) | SMN1; SMN2KMT2ALMNAMAPTATP4A | |
| SCHEMBL5879530 | 0.64 | CYP1A2 (0.50) | SMN1; SMN2HRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL16386106 | 0.64 | CYP2D6 (0.47) | SMN1; SMN2HRH2SLC22A2CA12SLC22A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SLCO1B3, SLC22A8, SLC10A6 | SMN1; SMN2 4777/4885KMT2A 3316/4885HRH2 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.