Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18199343 | 0.77 | F2 (0.58) | F2PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL21661932 | 0.72 | F2 (0.56) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1857920 | 0.69 | KDM4E (0.45) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL10331920 | 0.68 | F2 (0.65) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL10864671 | 0.67 | KDM4E (0.43) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL183325 | 0.67 | F2 (1.00) | F2PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL22490111 | 0.67 | F2 (0.50) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14165295 | 0.67 | F2 (0.52) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL30830443 | 0.65 | F2 (0.61) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20653206 | 0.65 | KDM4E (0.42) | KDM4EALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745274-B2 | Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SLCO1B3, SLC22A8, SLC10A6 | F2 4685/4885PRSS1 1126/4885PRSS2 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.