Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202495 | 0.87 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL18199577 | 0.81 | CHRM3 (0.79) | CHRM3MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20202494 | 0.69 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL18199587 | 0.68 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL20202493 | 0.68 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4203042 | 0.67 | KEAP1 (0.61) | CHRM3ALDH1A1CHRM2CHRM1 | |
| SCHEMBL4213705 | 0.67 | KEAP1 (0.61) | CHRM3ALDH1A1CHRM2CHRM1 | |
| SCHEMBL13928640 | 0.67 | CHRM3 (0.57) | CHRM3ALDH1A1CHRM2CHRM1 | |
| SCHEMBL4203592 | 0.67 | KEAP1 (0.61) | CHRM3ALDH1A1CHRM2CHRM1 | |
| SCHEMBL22899741 | 0.67 | CHRM3 (0.42) | CHRM3KDM4ECHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016173817-A1 | N-ARALKYLCARBONYL-PIPERAZINE AND -HOMOPIPERAZINE COMPOUNDS AND PERSONAL CARE COMPOSITIONS COMPRISING THE SAME | UNILEVER PLC (GB) | 2016-11-03 | — | — | WO | disclosed |