SCHEMBL18201341

SCHEMBL18201341

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2cc(-c3ccc4oc5ccccc5c4c3)cc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.45
PLA2G2A P14555 4/20 0.41
PLA2G4A P47712 4/20 0.41
PLA2G10 O15496 1/20 0.40
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.37
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSPO P30536 1/20 0.36
PRKDC P78527 3/20 0.36
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35
BRCA1 P38398 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22672160 1.00 KDM4E (0.45) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL17974254 0.97 KDM4E (0.41) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL11987373 0.97 KDM4E (0.47) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL20706818 0.97 PLA2G2A (0.43) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL16656492 0.97 PLA2G2A (0.43) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL16901368 0.97 PLA2G2A (0.43) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL11987367 0.97 PLA2G2A (0.43) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL30103830 0.97 PLA2G2A (0.43) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL20714952 0.96 PLA2G2A (0.41) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL20706883 0.96 PLA2G2A (0.43) KDM4EL3MBTL1ATMPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016175533-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-11-03 WO disclosed