SCHEMBL18201427

SCHEMBL18201427

c1ccc(-c2ccc(-c3ccc(Nc4ccc(-c5ccccn5)cn4)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.49
HCAR3 P49019 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
WNT3A P56704 2/20 0.44
KDR P35968 1/20 0.43
CNR2 P34972 1/20 0.42
GRM5 P41594 1/20 0.42
HPGDS O60760 1/20 0.41
PLK1 P53350 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12249871 0.83 CYP2A6 (0.48) CYP2A6MEN1KMT2ALMNAMAPT
SCHEMBL904463 0.81 MEN1 (0.55) MEN1KMT2AKDRNPC1RAB9A
SCHEMBL27040072 0.79 CSNK2A2 (0.57) HCAR3MAPTNPC1RAB9A
SCHEMBL31593145 0.79 CSNK2A2 (0.57) HCAR3MAPTNPC1RAB9A
SCHEMBL15158536 0.78 HSD17B10 (0.52) CYP2A6MEN1KMT2ALMNAMAPT
SCHEMBL4895714 0.78 TP53 (0.47) MEN1KMT2ALMNAMAPTKDR
SCHEMBL16200517 0.78 HPGDS (0.50) CYP2A6MEN1KMT2ALMNAMAPT
SCHEMBL31390266 0.77 MEN1 (0.59) MEN1KMT2A
SCHEMBL21012393 0.77 KDM4E (0.54) CYP2A6MEN1KMT2ALMNAMAPT
SCHEMBL11267993 0.77 CYP2A6 (0.50) CYP2A6LMNAMAPTWNT3ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016175533-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-11-03 WO disclosed