Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19291273 | 0.88 | KMT2A (0.49) | KMT2AMEN1ERN1L3MBTL1HSD17B1 | |
| SCHEMBL30036639 | 0.83 | L3MBTL1 (0.55) | KMT2AMEN1L3MBTL1HSD17B2NPC1 | |
| SCHEMBL322040 | 0.82 | KMT2A (0.53) | KMT2AMEN1ERN1L3MBTL1HSD17B1 | |
| SCHEMBL3996930 | 0.82 | KMT2A (0.53) | KMT2AMEN1ERN1L3MBTL1HSD17B1 | |
| SCHEMBL29866123 | 0.82 | KMT2A (0.53) | KMT2AMEN1ERN1L3MBTL1HSD17B1 | |
| SCHEMBL7044973 | 0.81 | FOLH1 (0.62) | KMT2AMEN1ERN1L3MBTL1HSD17B1 | |
| SCHEMBL30240849 | 0.81 | KMT2A (0.56) | KMT2AMEN1ERN1L3MBTL1HSD17B1 | |
| SCHEMBL3276164 | 0.81 | KMT2A (0.51) | KMT2AMEN1ERN1L3MBTL1HSD17B1 | |
| SCHEMBL29866166 | 0.81 | KMT2A (0.51) | KMT2AMEN1ERN1L3MBTL1HSD17B1 | |
| SCHEMBL5567925 | 0.81 | KMT2A (0.56) | KMT2AMEN1ERN1L3MBTL1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176473-A1 | APELIN RECEPTOR AGONISTS AND METHODS OF USE THEREOF | SANFORD-BURNHAM MEDICAL RESEARC INSTITUTE (US) | 2016-11-03 | — | — | WO | disclosed |