SCHEMBL18201983

SCHEMBL18201983

[N-]=[N+]=NC(=O)/C=C/c1cccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC8 Q9BY41 1/20 0.55
▸ HDAC6 Q9UBN7 1/20 0.55
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ MAPT P10636 2/20 0.50
▸ CYP1A1 P04798 2/20 0.50
▸ CYP1B1 Q16678 2/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ NPY1R P25929 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ NPY2R P49146 1/20 0.50
▸ NPC1 O15118 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ MTNR1A P48039 1/20 0.47
▸ MTNR1B P49286 1/20 0.47
▸ RXRA P19793 1/20 0.43
▸ PLK1 P53350 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13729150 0.78 HDAC1 (0.53) HDAC8HDAC6SMN1; SMN2MAPTCYP1A1
SCHEMBL13729148 0.78 HDAC1 (0.53) HDAC8HDAC6SMN1; SMN2MAPTCYP1A1
SCHEMBL14515064 0.77 BACE1 (0.62) HDAC8HDAC6SMN1; SMN2MAPTALDH1A1
SCHEMBL14515068 0.77 PARP1 (0.44) HDAC8HDAC6SMN1; SMN2MAPTALDH1A1
SCHEMBL5433951 0.77 HDAC8 (0.56) HDAC8HDAC6SMN1; SMN2MAPTCYP1A1
SCHEMBL22229994 0.77 CYP1A2 (0.40) HDAC8SMN1; SMN2MAPTALDH1A1CYP1A2
SCHEMBL5598861 0.77 HDAC8 (0.69) HDAC8HDAC6SMN1; SMN2MAPTCYP1A1
SCHEMBL3007219 0.77 HDAC8 (0.69) HDAC8HDAC6SMN1; SMN2MAPTCYP1A1
SCHEMBL15958497 0.76 PTGS2 (0.47) HDAC8HDAC6SMN1; SMN2MAPTCYP1A1
SCHEMBL23069115 0.75 HDAC8 (0.67) HDAC8HDAC6SMN1; SMN2MAPTCYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793064-B2 Organic metal complex, and organic light emitting device and display apparatus using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-17 — — US disclosed
US-20170092882-A1 ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-03-30 — — US disclosed
US-20170092882-A1 ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-03-30 — — US disclosed
US-9554442-B2 Organic metal complex, and organic light emitting device and display apparatus using the same CANON KABUSHIKI KAISHA (JP) 2017-01-24 — — US disclosed
US-9554442-B2 Organic metal complex, and organic light emitting device and display apparatus using the same CANON KABUSHIKI KAISHA (JP) 2017-01-24 — — US disclosed
EP-2217607-B1 ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME CANON KK (JP) 2016-11-02 — — EP disclosed
US-20100219407-A1 ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME CANON KABUSHIKI KAISHA (JP) 2010-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100219407-A1 ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME L1CAM, AP2M1, MRPL9 HDAC8 4803/4885HDAC6 4673/4885SMN1; SMN2 2326/4885
US-11793064-B2 Organic metal complex, and organic light emitting device and display apparatus using the same L1CAM, AP2M1, MRPL9 HDAC8 4803/4885HDAC6 4673/4885SMN1; SMN2 2326/4885
US-20170092882-A1 ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME L1CAM, AP2M1, MRPL9 HDAC8 4803/4885HDAC6 4673/4885SMN1; SMN2 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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