Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 18/20 | 0.82 |
| ▸ | SRC | P12931 | 13/20 | 0.73 |
| ▸ | SYK | P43405 | 13/20 | 0.73 |
| ▸ | MAPK14 | Q16539 | 13/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16829549 | 0.90 | GSK3A (1.00) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL18202140 | 0.89 | MAPK14 (0.84) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL16829563 | 0.86 | GSK3A (1.00) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL16829289 | 0.84 | MAPK14 (1.00) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL16829536 | 0.84 | GSK3A (1.00) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL16844915 | 0.84 | GSK3A (1.00) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL16106411 | 0.84 | GSK3A (0.72) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL16829190 | 0.83 | MAPK14 (1.00) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL17652762 | 0.83 | GSK3A (1.00) | GSK3ASRCSYKMAPK14 | |
| SCHEMBL16829443 | 0.82 | GSK3A (1.00) | GSK3ASRCSYKMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318958-A1 | UREA DERIVATIVES USEFUL AS KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318958-A1 | UREA DERIVATIVES USEFUL AS KINASE INHIBITORS | SYK, UACA, YES1 | GSK3A 853/4885SRC 6/4885SYK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.