SCHEMBL18202876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10594663	0.77	NUDT1 (0.41)	NUDT1JAK2KDM4EALDH1A1JAK1
	SCHEMBL3306356	0.77	NUDT1 (0.57)	TNK2NUDT1KDM4EALDH1A1JAK1
	SCHEMBL25646677	0.76	LRRK2 (0.40)	NUDT1LRRK2JAK1MTORPDE10A
	SCHEMBL3599442	0.75	NUDT1 (0.63)	CHEK1NUDT1JAK1AKT1AKT2
	SCHEMBL10594458	0.75	KDM4E (0.58)	NUDT1KDM4EALDH1A1SMN1; SMN2GAA
	SCHEMBL2256835	0.75	POLB (0.42)	NUDT1KDM4EALDH1A1JAK1NPC1
	SCHEMBL3584146	0.74	JAK1 (0.60)	JAK2KDM4EALDH1A1JAK1SMN1; SMN2
	SCHEMBL3297508	0.74	NUDT1 (0.39)	TNK2NUDT1JAK2KDM4EALDH1A1
	SCHEMBL10856202	0.72	NUDT1 (0.38)	NUDT1JAK2KDM4EALDH1A1JAK1
	SCHEMBL10594383	0.72	NUDT1 (0.48)	NUDT1KDM4EALDH1A1JAK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.