Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202979 | 0.99 | PLA2G7 (0.46) | PLA2G7HPGDPDK1PDK2PDK3 | |
| SCHEMBL18203030 | 0.80 | S1PR4 (0.46) | PDK1PDK2PDK3PDK4TSHR | |
| SCHEMBL18202971 | 0.72 | CLCN2 (0.37) | TSHRKMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL15499084 | 0.72 | HPGD (0.75) | PLA2G7HPGDTSHRKMT2APOLB | |
| SCHEMBL20838860 | 0.70 | HPGD (0.53) | PLA2G7HPGDKMT2AMAPTALDH1A1 | |
| SCHEMBL19088577 | 0.70 | HPGD (0.73) | PLA2G7HPGDTSHRKMT2APOLB | |
| SCHEMBL20838851 | 0.70 | HPGD (0.52) | HPGDKMT2AATMALDH1A1SMN1; SMN2 | |
| SCHEMBL18202972 | 0.69 | GRIA1 (0.42) | KMT2APOLBATMMAPTMEN1 | |
| SCHEMBL14438968 | 0.69 | HPGD (0.71) | PLA2G7HPGDTSHRKMT2APOLB | |
| SCHEMBL19088586 | 0.69 | HPGD (0.74) | PLA2G7HPGDTSHRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176449-A1 | BENZIMIDAZOLONE AND BENZOTHIAZOLONE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-11-03 | — | — | WO | disclosed |