Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 10/20 | 0.79 |
| ▸ | CACNG8 | Q8WXS5 | 9/20 | 0.79 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | WEE1 | P30291 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190698 | 0.89 | GRIA1 (1.00) | GRIA1CACNG8PDE3BPDE3AMAPT | |
| SCHEMBL18190398 | 0.82 | GRIA1 (0.79) | GRIA1CACNG8PDE3BPDE3AMAPT | |
| SCHEMBL18190602 | 0.82 | GRIA1 (1.00) | GRIA1CACNG8PDE3BPDE3AMAPT | |
| SCHEMBL18190537 | 0.82 | GRIA1 (0.79) | GRIA1CACNG8PDE3BPDE3AMAPT | |
| SCHEMBL21900282 | 0.81 | GRIA1 (0.73) | GRIA1CACNG8ALDH1A1GRIK1GRIA2 | |
| SCHEMBL18190610 | 0.79 | GRIA1 (0.75) | GRIA1CACNG8PDE3BPDE3AMAPT | |
| SCHEMBL18190701 | 0.78 | GRIA1 (0.73) | GRIA1CACNG8PDE3BPDE3AMAPT | |
| SCHEMBL18190666 | 0.78 | GRIA1 (1.00) | GRIA1CACNG8PDE3BPDE3A | |
| SCHEMBL18190563 | 0.78 | GRIA1 (0.73) | GRIA1CACNG8PDE3BPDE3AKMT2A | |
| SCHEMBL18190647 | 0.78 | GRIA1 (1.00) | GRIA1CACNG8PDE3BPDE3ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176449-A1 | BENZIMIDAZOLONE AND BENZOTHIAZOLONE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-11-03 | — | — | WO | disclosed |