Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 9/20 | 0.69 |
| ▸ | CACNG8 | Q8WXS5 | 9/20 | 0.69 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CDC25C | P30307 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190758 | 0.85 | GRIA1 (0.67) | GRIA1CACNG8PDE3BPDE3ADRD2 | |
| SCHEMBL18190411 | 0.82 | GRIA1 (1.00) | GRIA1CACNG8PDE3BPDE3ADRD2 | |
| SCHEMBL18203048 | 0.72 | GRIA1 (0.51) | GRIA1CACNG8DRD2CDC25ACDC25B | |
| SCHEMBL18190646 | 0.70 | GRIA1 (1.00) | GRIA1CACNG8PDE3BPDE3AGAA | |
| SCHEMBL18190641 | 0.68 | GRIA1 (0.67) | GRIA1CACNG8PDE3BPDE3ADYRK1A | |
| SCHEMBL18190531 | 0.68 | GRIA1 (0.70) | GRIA1CACNG8PDE3BPDE3ADRD2 | |
| SCHEMBL18190763 | 0.67 | GRIA1 (0.73) | GRIA1CACNG8PDE3BPDE3ADRD2 | |
| SCHEMBL18190698 | 0.67 | GRIA1 (1.00) | GRIA1CACNG8PDE3BPDE3ADYRK1A | |
| SCHEMBL18190577 | 0.66 | GRIA1 (0.81) | GRIA1CACNG8PDE3BPDE3AMAPT | |
| SCHEMBL18203057 | 0.66 | GRIA1 (0.66) | GRIA1CACNG8PDE3BPDE3AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176449-A1 | BENZIMIDAZOLONE AND BENZOTHIAZOLONE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-11-03 | — | — | WO | disclosed |