Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1816821 | 0.78 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19L3MBTL1CA12 | |
| SCHEMBL1820338 | 0.78 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19L3MBTL1CA12 | |
| SCHEMBL1818154 | 0.77 | CA12 (0.51) | CYP1A2CYP2C9CYP2C19L3MBTL1CA12 | |
| SCHEMBL1815977 | 0.75 | CA12 (0.46) | CYP1A2CYP2C9CYP2C19L3MBTL1CA12 | |
| SCHEMBL1816870 | 0.74 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19L3MBTL1CA12 | |
| SCHEMBL2190229 | 0.73 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19L3MBTL1CA12 | |
| SCHEMBL1819456 | 0.73 | CYP2C9 (0.40) | CYP1A2CYP2C9CYP2C19L3MBTL1CA12 | |
| SCHEMBL1819630 | 0.73 | L3MBTL1 (0.71) | CYP1A2CYP2C9CYP2C19L3MBTL1SMN1; SMN2 | |
| SCHEMBL1820493 | 0.73 | CA12 (0.43) | CYP1A2CYP2C9CYP2C19L3MBTL1CA12 | |
| SCHEMBL1819384 | 0.72 | L3MBTL1 (0.44) | CYP1A2CYP2C9CYP2C19L3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461134-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110172187-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| WO-2011060196-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172187-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, BTD | CYP1A2 3504/4885CYP2C9 3001/4885CYP2C19 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.