Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.78 |
| ▸ | NQO2 | P16083 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tepotinib SCHEMBL29379106 | 0.88 | MET (1.00) | METNQO2 | |
| Tepotinib SCHEMBL1296895 | 0.88 | MET (1.00) | METNQO2 | |
| SCHEMBL2527890 | 0.87 | MET (0.80) | METNQO2 | |
| Tepotinib SCHEMBL29550043 | 0.87 | MET (0.98) | METNQO2 | |
| Tepotinib SCHEMBL1296467 | 0.87 | MET (0.98) | METNQO2 | |
| Tepotinib SCHEMBL30259391 | 0.87 | MET (0.98) | METNQO2 | |
| Tepotinib SCHEMBL1295616 | 0.87 | MET (0.98) | METNQO2 | |
| SCHEMBL2530219 | 0.84 | MET (0.84) | METNQO2 | |
| SCHEMBL3088622 | 0.84 | MET (0.80) | METNQO2 | |
| SCHEMBL2457792 | 0.84 | MET (0.80) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160324855-A1 | COMBINATION OF A 6-OXO-1,6-DIHYDRO-PYRIDAZINE DERIVATIVE HAVING ANTI-CANCER ACTIVITY WITH GEFITINIB | MERCK PATENTE GMBH (DE) | 2016-11-10 | — | — | US | claimed |