SCHEMBL18205264

SCHEMBL18205264

O=S(=O)(O)c1ccc2ccc3cccc4ccc1c2c34.[NaH].[NaH]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.49
AURKB Q96GD4 1/20 0.49
CTRB1 P17538 1/20 0.46
ALDH1A1 P00352 5/20 0.46
HPGD P15428 5/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPT P10636 1/20 0.46
CYP1A2 P05177 5/20 0.46
ERBB2 P04626 1/20 0.46
FYN P06241 1/20 0.46
MAOA P21397 1/20 0.46
ACHE P22303 1/20 0.46
AHR P35869 1/20 0.46
HSD17B10 Q99714 4/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TTR P02766 2/20 0.43
FABP4 P15090 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27783050 1.00 AURKA (0.49) AURKAAURKBCTRB1ALDH1A1HPGD
SCHEMBL592126 1.00 AURKA (0.49) AURKAAURKBCTRB1ALDH1A1HPGD
SCHEMBL29825144 0.98 AURKA (0.50) AURKAAURKBCTRB1ALDH1A1HPGD
SCHEMBL139959 0.98 AURKA (0.50) AURKAAURKBCTRB1ALDH1A1HPGD
SCHEMBL29623330 0.98 AURKA (0.50) AURKAAURKBCTRB1ALDH1A1HPGD
SCHEMBL28203347 0.98 AURKA (0.50) AURKAAURKBCTRB1ALDH1A1HPGD
SCHEMBL592128 0.96 AURKA (0.49) AURKAAURKBCTRB1ALDH1A1HPGD
Hydrochloric Acid SCHEMBL11162639 0.96 CTRB1 (0.50) AURKAAURKBCTRB1ALDH1A1HPGD
Water SCHEMBL29714759 0.96 AURKA (0.49) AURKAAURKBCTRB1ALDH1A1HPGD
Water SCHEMBL14688267 0.96 AURKA (0.49) AURKAAURKBCTRB1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10144212-B2 Ink formulation THE UNIVERSITY OF MANCHESTER (GB) 2018-12-04 US disclosed
US-20160325543-A1 INK FORMULATION THE UNIVERSITY OF MANCHESTER (GB) 2016-11-10 US disclosed