Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28413106 | 1.00 | EPHX1 (0.56) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL1394898 | 1.00 | EPHX1 (0.56) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL20993755 | 1.00 | EPHX1 (0.56) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL28427707 | 0.97 | — | — | |
| SCHEMBL5624085 | 0.97 | — | — | |
| SCHEMBL10079176 | 0.97 | — | — | |
| SCHEMBL936012 | 0.92 | — | — | |
| SCHEMBL1678475 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL14744247 | 0.83 | — | — | |
| SCHEMBL23046648 | 0.83 | EPHX1 (0.40) | EPHX1TP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111362809-B | Chiral perovskite nanosheet, and preparation method and application thereof | 国家纳米科学中心 | 2023-03-31 | — | — | CN | claimed |
| CN-111362809-A | Chiral perovskite nanosheet, and preparation method and application thereof | 国家纳米科学中心 | 2020-07-03 | — | — | CN | claimed |
| CN-111362809-B | Chiral perovskite nanosheet, and preparation method and application thereof | 国家纳米科学中心 | 2023-03-31 | — | — | CN | disclosed |
| CN-111362809-A | Chiral perovskite nanosheet, and preparation method and application thereof | 国家纳米科学中心 | 2020-07-03 | — | — | CN | disclosed |
| EP-1735286-B1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-04 | — | — | EP | disclosed |
| CN-1956964-B | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV | 2011-06-15 | — | — | CN | disclosed |
| US-20090099143-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | LAGU BHARAT | 2009-04-16 | — | — | US | disclosed |
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |
| CN-1956964-A | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2007-05-02 | — | — | CN | disclosed |
| US-20050228034-A1 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228034-A1 | Tetrahydro-indazole cannabinoid modulators | CNR2, CNR1, GPR18 | EPHX1 969/4885TP53 4869/4885KDM4E 1714/4885 |
| US-20090099143-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | CNR2, CNR1, GPR18 | EPHX1 969/4885TP53 4869/4885KDM4E 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.