Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10826128 | 0.83 | POLB (0.61) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 | |
| SCHEMBL6191726 | 0.82 | PDE7A (0.62) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 | |
| SCHEMBL30876805 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 | |
| SCHEMBL29900473 | 0.82 | PDE7A (0.62) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 | |
| SCHEMBL29900461 | 0.82 | MEN1 (0.60) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 | |
| SCHEMBL23092512 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 | |
| SCHEMBL8781039 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 | |
| SCHEMBL29900515 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 | |
| SCHEMBL9934096 | 0.82 | POLB (0.56) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 | |
| SCHEMBL19332390 | 0.82 | MEN1 (0.60) | ALDH1A1CYP3A4POLBCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461134-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110172187-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| WO-2011060196-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172187-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, BTD | ALDH1A1 4190/4885CYP3A4 3430/4885POLB 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.