Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | IDUA | P35475 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.37 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glucuronate SCHEMBL28919162 | 0.92 | IDUA (0.41) | CA3CA14ALDH1A1CA6IDUA | |
| Glucuronate SCHEMBL28065767 | 0.92 | IDUA (0.41) | CA3CA14ALDH1A1CA6IDUA | |
| Glucuronate SCHEMBL28065814 | 0.92 | IDUA (0.41) | CA3CA14ALDH1A1CA6IDUA | |
| Glucuronate SCHEMBL6945670 | 0.86 | IDUA (0.38) | CA3CA14HIF1AALDH1A1CA6 | |
| Glucuronate SCHEMBL25253417 | 0.78 | IDUA (0.50) | HIF1AALDH1A1HSD17B10IDUACA12 | |
| Glucuronate SCHEMBL21792734 | 0.78 | IDUA (0.50) | HIF1AALDH1A1HSD17B10IDUACA12 | |
| Glucuronate SCHEMBL14406475 | 0.78 | IDUA (0.50) | HIF1AALDH1A1HSD17B10IDUACA12 | |
| Glucuronate SCHEMBL22749019 | 0.78 | IDUA (0.50) | HIF1AALDH1A1HSD17B10IDUACA12 | |
| Glucuronate SCHEMBL21312643 | 0.78 | IDUA (0.50) | HIF1AALDH1A1HSD17B10IDUACA12 | |
| Glucuronate SCHEMBL18163135 | 0.78 | IDUA (0.50) | HIF1AALDH1A1HSD17B10IDUACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8506947-B2 | Vaccinia virus expression vector for selective replication in a tumor cell and introduction of exogenous nucleotide sequence into a tumor cell | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-08-13 | — | — | US | disclosed |
| EP-2325321-A1 | A combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-05-25 | — | — | EP | disclosed |
| US-20070154458-A1 | Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector | The Gov. of the USA as represented by the Sec. of the Dep. of Health & Human Services, | 2007-07-05 | — | — | US | disclosed |
| US-7208313-B2 | Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-04-24 | — | — | US | disclosed |
| US-20030031681-A1 | Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT HEALTH AND HUMAN SERVICES, THE | 2003-02-13 | — | — | US | disclosed |