⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413238 | 1.00 | — | — | |
| SCHEMBL11026397 | 0.97 | IDO1 (0.54) | — | |
| SCHEMBL2045881 | 0.97 | IDO1 (0.54) | — | |
| SCHEMBL9230115 | 0.85 | NPC1 (0.44) | — | |
| SCHEMBL29447950 | 0.79 | TAAR1 (0.60) | — | |
| SCHEMBL490393 | 0.79 | PNMT (0.62) | — | |
| SCHEMBL320795 | 0.79 | TAAR1 (0.60) | — | |
| SCHEMBL29382225 | 0.78 | TSHR (0.50) | — | |
| SCHEMBL28289 | 0.78 | TSHR (0.50) | — | |
| SCHEMBL1294517 | 0.77 | TAAR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2448 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354962-B | 12-Nitrogen substituted matric acid ester derivative, preparation method and application thereof | 广西大学 | 2025-01-07 | — | — | CN | claimed |
| CN-119101052-A | Matrine-triazole derivative and synthesis method thereof | 吉林医药学院 | 2024-12-10 | — | — | CN | claimed |
| CN-118221691-B | Methylenedioxybenzo [ b ] [1,4] diazepine [5,6-e ] triazinone derivative and pharmaceutically acceptable salt, preparation method and application thereof | 常熟理工学院 | 2024-10-15 | — | — | CN | claimed |
| CN-114957238-B | 3-hydroxy-pyrrole-2-ketone compound containing 1,3, 4-thiadiazole and synthetic method and application thereof | 南京工业大学 | 2024-02-06 | — | — | CN | claimed |
| CN-117247379-A | Preparation method of high-purity difenoconazole | 山东潍坊双星农药有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-116715624-A | Synthesis method of N-alkylated pyrithione compound | 信阳师范学院 | 2023-09-08 | — | — | CN | claimed |
| CN-116354962-A | 12-nitrogen substituted matric acid ester derivative, preparation method and application thereof | 广西大学 | 2023-06-30 | — | — | CN | claimed |
| CN-112047928-B | Isonicotinamide AChE-GSK3 double inhibitor and preparation method and application thereof | 中国药科大学 | 2022-09-23 | — | — | CN | claimed |
| CN-114957238-A | 3-hydroxy-pyrrole-2-ketone compound containing 1,3, 4-thiadiazole and synthetic method and application thereof | 南京工业大学 | 2022-08-30 | — | — | CN | claimed |
| WO-2021047572-A1 | GSK-3β/CHE DOUBLE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2021-03-18 | — | — | WO | claimed |
| WO-2012040845-A1 | PROCESS FOR THE PREPARATION OF TETRACYCLIC DERIVATIVES AND INTERMEDIATE PRODUCTS USED IN THE PROCESS | ALPHORA RESEARCH INC. (CA) | 2012-04-05 | — | — | WO | claimed |
| US-20110039895-A1 | PROLYL HYDROXYLASE INHIBITORS | Glaxo Smith Kline LLC., a corporation | 2011-02-17 | — | — | US | claimed |
| EP-2273879-A1 | PROLYL HYDROXYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2011-01-19 | — | — | EP | claimed |
| CN-100999449-B | Preparation method of aliphatic cyclo benzylether | DALIAN LIANHUA MEDICAL TECHNOLOGY CO LTD | 2010-05-19 | — | — | CN | claimed |
| WO-2009134850-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-11-05 | — | — | WO | claimed |
| CN-100999449-A | Preparation method of aliphatic cyclo benzylether | DALIAN LIANHUA MEDICAL TECHNOL (CN) | 2007-07-18 | — | — | CN | claimed |
| US-7001973-B2 | Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups | DEGUSSA AG (DE) | 2006-02-21 | — | — | US | claimed |
| EP-0918783-A1 | 6-O-SUBSTITUTED ERYTHROMYCINS AND METHOD FOR MAKING THEM | ABBOTT LABORATORIES (US) | 1999-06-02 | — | — | EP | claimed |
| WO-1997042204-A1 | 6-O-SUBSTITUTED ERYTHROMYCINS AND METHOD FOR MAKING THEM | ABBOTT LABORATORIES (US) | 1997-11-13 | — | — | WO | claimed |
| US-5565602-A | REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-15 | — | — | US | claimed |