SCHEMBL18211595

SCHEMBL18211595

CCCCCCCNC(=O)c1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALB P02768 2/20 0.59
HTRA2 O43464 7/20 0.57
HTRA1 Q92743 7/20 0.57
FOLH1 Q04609 1/20 0.54
USP2 O75604 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
DNASE1L3 Q13609 1/20 0.53
PRMT1 Q99873 1/20 0.53
ESR1 P03372 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18162919 1.00 ALB (0.59) ALBHTRA2HTRA1FOLH1USP2
SCHEMBL13286956 0.99 ALB (0.60) ALBHTRA2HTRA1FOLH1USP2
SCHEMBL13287065 0.93 USP2 (0.60) ALBFOLH1USP2L3MBTL1ESR1
SCHEMBL13286952 0.93 USP2 (0.57) ALBHTRA2HTRA1FOLH1USP2
SCHEMBL12123525 0.92 ALB (0.60) ALBHTRA2HTRA1FOLH1USP2
SCHEMBL18162918 0.92 ALB (0.64) ALBHTRA2HTRA1FOLH1USP2
SCHEMBL12675193 0.92 ALB (0.58) ALBHTRA2HTRA1FOLH1USP2
SCHEMBL24062674 0.92 ALB (0.59) ALBHTRA2HTRA1FOLH1USP2
SCHEMBL25698357 0.90 ALB (0.57) ALBHTRA2HTRA1FOLH1USP2
SCHEMBL24943566 0.90 ALB (0.61) ALBHTRA2HTRA1FOLH1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160326576-A1 DUAL QUENCHER PROBES BIOSEARCH TECHNOLOGIES, INC. 2016-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160326576-A1 DUAL QUENCHER PROBES DNA2, WRN, DDX42 ALB 4779/4885HTRA2 267/4885HTRA1 1409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.